RESULTS
Kinetics of IL-17 protein expression in PBMC from healthy donors
This initial study was performed to confirm the ability of B. pseudomallei and B. thailandensis to induce the expression of IL-17 by PBMC of healthy donors (n = 10) at 3, 6, 18, and 24 hours (Fig. 1). A significant increase in IL-17 expression was noted with B. thailandensis (p < 0.05) but not with B. pseudomallei as compared to unstimulated PBMC at 18 and 24 hours. It was unexpected to observe this significantly higher expression of IL-17 in PBMC stimulated with B. thailandensis compared to those stimulated with B. pseudomallei at 18 (p < 0.05) and 24 hours (p < 0.01) (Fig. 1).