The gout initial therapy is performed with drugs such as colchicine,
nonsteroidal anti-inflammatory (NSAIDs) and oral corticosteroids.
In addition, there are drugs that act on the hyperuricemia
development process. Some of them can reduce the endogenous production of uric acid, as allopurinol. Others like probenecid
and benzbromarone increase uric acid elimination and are
called uricosuric agents, useful in underexcreters patients. However,
these drugs have been associated with adverse effects including
renal and gastrointestinal toxicity