he TRC is a curriculum-wide E-learning program which helps the student understand pharmacological mechanisms of action. Each mechanism is displayed by a graphic using unique TRC symbols, which contribute to a better understanding. This is accompanied by explanatory text with examples and links to drug formularies and other drug mechanisms. The mechanisms are presented in the context of (patho)physiological processes. The student can assess his knowledge by answering the short questions and learn from the feedback. Besides the drug mechanisms, the TRC also explains basic pharmacodynamic and -kinetic topics. For the application of the pharmacological knowledge, the students can practice writing therapeutic plans according the 6STEP methodology. About 40 cases are available with different stages of complexity; from beginners towards advanced cases. The TRC has various user-friendly functionalities such as personalisation (each user has its own TRC page), search function, and 6STEP portfolio.