The uptake of drugs from the thigh is slower than from the arm. The thigh may be used when the other sites are not available or if a patient needs to administer the medication on their own while lying down. A ventrogluteal site such as the buttocks is the safest site for adults and children over seven months of age. It is deep and not close to any major blood vessels and nerves. The thigh is preferred for immunizations in children. The deltoid in the arm is the site most typically used for vaccines. It is rarely used for other medications because the volume of medication is too large.