The compounds, inhaled through the nasal cavity, enter the body through the olfactory epithelium via olfactory receptors.
Some molecules may be absorbed via the lungs into the body. To elucidate the pathway behind the effect of diacetone alcohol on locomotor activity, olfactory epithelium in mice was impaired using zinc sulfate. Two days after the treatment with zinc sulfate,mice showed lower locomotor activity than untreated mice, but exhibited no abnormal behaviors. The severity of smell disorders was examined by an acetic acid test