An intriguing result is that in the degraded granules (Fig. 1H), the staining heterogeneity is significant within single granules. As indicated by the white arrow, the central region of the granules stains with a different hue of blue, suggesting there may be structural differences within this region. According to findings of Parker et al. (2008), the level of staining is proportional to amylose content, hence the data in Fig. 1 could be attributed to the different concentration of amylose in some regions following the process of degradation.