As the presence of cellular protrusion,
called filopodia, has been indicated as a hallmark of
migrating cells, we showed that the reduction of the
mentioned proteins correlated well with the disappearance
of filopodia. In summary, this study demonstrates the
promising activity of TDB and its mechanism in the inhibition
of lung cancer cell migration, which might be useful
for encouraging the development of this compound for
antimetastatic approaches.