In this work, we develop a 5-HT sensitive LAPS sensor for serotonin
detection from taste cells and taste epithelium. Its flexibility,
addressability, planar structure and good performance are suitable
for investigation of taste cell-to-cell communication. Immunofluorescent
imaging assay proves its feasibility and ensures that there
are both functional type II and III taste cells in isolated taste clusters.
Results indicate that serotonin should play essential roles in
taste information transmission. This 5-HT sensitive LAPS sensor
opens up a new direction for neurotransmitter detection and the
investigation of taste information communication mechanisms.
Acknowledgements
This work was supported by the grants