In vivo efficacy of lupeol
Male BALB/c nude mice at 4 weeks of age (Shanghai SLAC Laboratory Animal Center of Chinese Academy of Sciences, Shanghai, China) were maintained throughout in specific pathogen-free (SPF) environment. Exponentially growing PCNA-1 cells (5×106) were suspended in 150 μL PBS and subcutaneously injected into the right axillary fossa of each nude mouse