To prepare the vaginal cream at concentrations of 0.5, 1.0 and 2.0% of extract (w/w), we used a formula derived from an oil/water emulsion. Aqueous and oily phases were heated separately to 75 °C for complete melting of the fatty material, pooled, and stirred until cool for incorporation of the extract, previously dissolved in propylene glycol. This cream was prepared without a preservative.