Abstract: The failure of Doha Round is a serious step backward for the WTO and the multilateral trading system. Some analysts already discussed in their research about the round as being already closed and they propose the developing of a new program within the organization. WTO still remains a very important institution due to its proven role in encouraging states not to take protectionist measures during the recent economic crisis, but the global trade governance reform must reflect all the changes and realities. The transition is being made toward a more regionalized and preferential global trade and the emergence of strong developing countries shape the whole multilateral trade negotiations. The important growth rates in emerging countries are translated also in strong demand for representation in global trade governance. Objectives: This paper aims to underline the role of multilateralism as form of international cooperation, the link with global economic governance and what concerns academic community in terms of having a reform of it. Prior Work: It has been tried to emphasizing the concepts already developed by known researchers in the field. Approach: The approach is a more theoretic one done in a comparative manner with emphasis on results and future research. The critical method approach is done with qualitative results. Results: The key results are related to pros and cons of reforming the World Trade Organization, as well as presenting the criticisms and proposals for having a second World Trade Organization. Implications: The implications are varied in terms of studying the concepts and addresses researchers in the field, but also lecturers and students. Value: The main added value is the compared approach of the traditional WTO as it derived from General Agreement on Tariff and Trade and the proposal for a new one and its formal relationship with the global economic governance.