In peptic ulcer this is also observed. In a study conducted by Mentz and Schenkel20, in which they assessed plants with popularly known effects to scientifically prove them, they observed that plants like Symphytum Officinale L. (Comfrey), besides having no proven efficacy it may be harmful because of their pyrrolizidine alkaloids, of proven hepatotoxic action. Another studied plant was Zantoxylon rhoifoliun Lan (“mamica-de-cadela”), popularly indicated for ulcers and healing, but its benefits have not been proved either. In addition, Maytenus ilicifolia Mart, commonly known in Brazil as “espinheira-santa”, used for healing peptic ulcer, has not proven this effect in trials either. Studied the effects of Peumus boldus (“boldo”) and Baccharis genistelloides (“carqueja”), both commonly used to treat digestive problems and ulcers. The studies that proved various activities popularly attributed to these plants are associated with the isolate chemical compounds, such as, for example, flavonoids, antioxidants found both in boldo and carqueja leaves. However, the benefits of these teas in the cure of peptic ulcer have not been scientifically proven27. The use of natural products in treatment of ulcer has been widely studied. However, most of the studies7 that have proven an anti-ulcer effect were conducted with animals, and therefore do not provide reliability for alternative treatments in the prevention of relapses or for treatment of peptic ulcer in humans.