In addition, the amino-acidic nature of silk fibroin brings a diversity of side chain chemistries
that allows for the incorporation of macromolecules useful in drug delivery applications or in providing cellular
instructions. The natural properties of silk fibroin have been exploited in the regenerated silk materials.
The combination of beta-sheet structures with inter- and intra-molecular hydrogen bonds that provides
high-flexibility in the natural fibre also guarantees extreme conformability in regenerated film format. Silk fibroin
films have in fact been used as biocompatible and biodegradable substrates for implantable electrodes to be
applied on the brain and as adhesive, edible sensors to monitor fruit ripening and cheese aging