We identified group regional activations related to a naturally occurring, emotionally chaotic, motivational state that may have value for survival and reproduction, namely to win back a mate. We do not know whether the activation in the VTA, nucleus accumbens, and an extended forebrain gain/loss system in this group of individuals was adaptive or maladaptive for them, but it indicates the motivational relevance of the rejecter. Also the involvement of the dopamine-rich mesolimbic regions suggest behavior associated with romantic rejection has a basis in mammalian, (not only human) drives. Thus this brain imaging study of individuals who were still “in love” with their rejecter supplies further evidence that the passion of “romantic love” is a goal-oriented motivation state rather than a specific emotion (Aron and Aron 1991; Aron et al. 2005). Moreover, the fMRI results of the study show that looking at a romantic rejecter and cocaine craving have several neural correlates in common. The findings are consistent with the hypothesis that romantic rejection is a specific form of addiction (Fisher 2004). The perspective that rejection in love involves subcortical reward gain/loss systems critical to survival helps to explain why feelings and behaviors related to romantic rejection are difficult to control and lends insight into the high cross-cultural rates of stalking, homicide, suicide, and clinical depression associated with rejection in love.