2.2. Fermentation
Fed-batch and continuous fermentation have offered substantial
improvements in volumetric productivity compared to simple batch fermentation [4,9,17–20]. However, fed-batch fermentation
requires in situ product recovery, while for continuous fermentation
multiple reactors are required to achieve a reasonable product
concentration [4]. Another means to improve the continuous fermentation
process is to apply cell recycle or immobilization of
cells, but none of these technologies have been implemented on
industrial scale [9]. Therefore fed-batch fermentation, reliant on
an in situ product recovery technique, and repeated batch fermentation,
rendering an overall semi-continuous process, was chosen
for process modeling.
2.2. FermentationFed-batch and continuous fermentation have offered substantialimprovements in volumetric productivity compared to simple batch fermentation [4,9,17–20]. However, fed-batch fermentationrequires in situ product recovery, while for continuous fermentationmultiple reactors are required to achieve a reasonable productconcentration [4]. Another means to improve the continuous fermentationprocess is to apply cell recycle or immobilization ofcells, but none of these technologies have been implemented onindustrial scale [9]. Therefore fed-batch fermentation, reliant onan in situ product recovery technique, and repeated batch fermentation,rendering an overall semi-continuous process, was chosenfor process modeling.
การแปล กรุณารอสักครู่..
