The complete suppression
of its acidity converts K-Oxyma into the most suitable coupling
choice when peptides are assembled in highly acid-labile
solid-supports. The coupling efficiency and epimerisation reduction
ability are conserved with regard to the parent OxymaPure.
In addition, K-Oxyma displays great solubility in water and a
variety of organic solvents and is safer than classical 1-hydroxybenzotriazole
additives.