In addition, pathological examinations revealed the vacuolar
changes of the nuclei in renal tubular epithelial cells,
probably resulting by intranuclear glycogen accumulation
because of positive to PAS staining. These findings are very
similar to a previous report of renal lesions suspected as
being WHS specific [2]. Present findings indicate that the
vacuolation of the nuclear lesions of the renal tubular epithelial
cells may not be specific for WHS in African hedgehogs.
The relevance of these renal findings and the CNS
lesions is unidentified at present, and more cases of various
CNS diseases of hedgehogs are necessary