Hydrogen peroxide (H2O2) is an oxygen metabolite and has dual role in the living system. It has been considered as a “necessary evil” due to the fact that it involves in the redox signaling for the normal function and it is an unwanted “killing agent”. The abnormal gener- ation of H2O2 induces oxidative stress and is associated with aging and cancer [1]. In recent years, many methods have been reported for the determination of H2O2, such as electrochemistry [2–4], chemiluminescence [5], and fluorescence [6,7]. However, they suf- fer from serious drawbacks such as time-consuming fabrication procedures and the need for expensive reagents, etc. Compared to the above analytical techniques, the colorimetric assay is simple, low-cost and practical. Moreover, the detection of analytes can also be immediately observed by the naked eye. At present, colorimet- ric method for H2O2 detection have been reported [8,9], but they suffered from poor detection limit. Thus, there is an ever-growing demand to create rapid, high sensitive and low cost H2O2 sensors.
Noble metals such as Au and Ag nanoparticles (NPs) possess
strong surface plasmon resonance (SPR) absorption from the visible to near-infrared region. Moreover, the SPR absorption is extremely sensitive to their size, shape, and distance, based on which various colorimetric sensors have been developed [9–14]. In contrast to Au NPs, Ag NPs exhibit certain advantages. First, silver is much cheaper
Hydrogen peroxide (H2O2) is an oxygen metabolite and has dual role in the living system. It has been considered as a “necessary evil” due to the fact that it involves in the redox signaling for the normal function and it is an unwanted “killing agent”. The abnormal gener- ation of H2O2 induces oxidative stress and is associated with aging and cancer [1]. In recent years, many methods have been reported for the determination of H2O2, such as electrochemistry [2–4], chemiluminescence [5], and fluorescence [6,7]. However, they suf- fer from serious drawbacks such as time-consuming fabrication procedures and the need for expensive reagents, etc. Compared to the above analytical techniques, the colorimetric assay is simple, low-cost and practical. Moreover, the detection of analytes can also be immediately observed by the naked eye. At present, colorimet- ric method for H2O2 detection have been reported [8,9], but they suffered from poor detection limit. Thus, there is an ever-growing demand to create rapid, high sensitive and low cost H2O2 sensors.Noble metals such as Au and Ag nanoparticles (NPs) possessstrong surface plasmon resonance (SPR) absorption from the visible to near-infrared region. Moreover, the SPR absorption is extremely sensitive to their size, shape, and distance, based on which various colorimetric sensors have been developed [9–14]. In contrast to Au NPs, Ag NPs exhibit certain advantages. First, silver is much cheaper
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