Electrochemical characterization of the GNS–AuNP–CPE electrode surfacewas carried out by cyclic voltammetry, electrochemical
impedance spectroscopy, chronocoulometry, and adsorptive stripping differential pulse voltammetry
This study shows that oxidation of rivastigmine is facilitated at the GNS–AuNP–CPE electrode and remarkably increase in
current compared to the bare electrode due to enhanced adsorption of the former on electrode surface
Under the optimized conditions, the peak current (Ip) is found to be proportional to the RIV concentration in the
range of 2.0 × 10–7–6.0 × 10−4 M with a detection limit of 5.3 × 10−8 M. The proposed sensor shows a very
high level of sensitivity, selectivity, and a very good reproducibility for RIV determination. A good recovery
level obtained for real samples suggests practical utility of the GNS–AuNP–CPE as an effective and reliable electrochemical
sensor for RIV detection.