INTRODUCTION
Dysfunctional uterine bleeding (DUB) is
irregular uterine bleeding that occurs in the
absence of recognizable pelvic pathology,
general medical disease, or pregnancy. The
bleeding is unpredictable in many ways. It
may cause menorrhagia and is a common
problem in women of reproductive age. It
has been estimated that 10 to 15 percent of
women are afflicted with menorrhagia (6).
It is also responsible for more than 1/3 of
the annual hysterectomies (1, 2). Excessive
menstrual bleeding is one of the major
causes of morbidity in women affecting 1
in 5 women worldwide. It is also
responsible for 21% of gynecology
referrals (3). Menorrhagia is defined as
blood loss of greater than 80 ml or lasting
longer than 7 days. It is often seen among
women who are older than 35 years of age
(6). Most of current medical treatments are
either ineffective or expensive (4, 5). In
approximately 50% of patients no
pathological cause is found and the
diagnosis of dysfunctional uterine bleeding
(DUB) is made