A potential source of morbidity and possibly mortality from daily hemodialysis is vascular access failure as vascular access complications can have grave consequences [14, 15]; therefore, it is important to determine the effects of frequent cannulation on the vascular access. Arteriovenous grafts may be especially susceptible to early failure since punctures in the grafted material may weaken and eventually undermine the integrity of the access. A secondary consideration is the potential for increased medical costs if daily dialysis increases the number of access procedures necessary to maintain access patency. Patient acceptance of daily dialysis therapies may be impaired if the effects on vascular access patency are unknown since access complications are also a significant source of patient morbidity through pain associated with procedures and increased hospitalizations due to access failure. Finally, since arteriovenous fistulae are associated with improved survival in epidemiological studies [16], failure of the arteriovenous access may lead to increased mortality rates.