Lewis eventually ended up in Memphis, Tennessee, where he found work as a studio musician for Sun Studios. In 1956, he recorded his first single, a cover of Ray Price's "Crazy Arms," which did well locally. Lewis also worked on some recording sessions with Carl Perkins. While working at Sun, he and Perkins jammed with Elvis Presley and Johnny Cash. This session by the "Million Dollar Quartet" was recorded at the time, but it was not released until much later.