nts in various conditions (Gogoi et al., 2008).
The anti-inflammatory activities of the methanol extract
of D. indica leaves were observed in various experimental models.
In case of carrageenan-induced paw edema doses of 200 and 400
mg/kg of the extract significantly inhibited the percent increase in
reaction time while acetic acid induced capillary permeability. All
doses of extract and Indomethacin at a dose of 20 mg/kg showed a
significant decrease in dye leaking in the peritoneal fluid. The
methanolic extract of D. indica at 200 and 400 mg/kg showed a
significant anti-inflammatory activity and the possible mechanism
might be inhibition of mediator release and PG biosynthesis
(Yeshwante et al., 2009). A glycolic extract of D. indica prepared
from the mature fruits of the plant showed significant wound
healing activity alone or in combination with microcurrent
stimulation to skin wounds surgically induced on the back of
Wistar rats. It is mentioned that the result probably due to the
efficacy of microcurrent application since the extract alone did not
significantly accelerate the healing process. D. indica fruit extract
is most likely participates in the wound healing process as a result
of its anti-inflammatory properties (Domenico et al., 2011)