.2.2 Leukemia
This subtopic presents Acute Leukemia is the cancer that is the most common malignant disease affecting children. Acute Leukemia has a peak bimodal age distribution in children between 2 and 5 years old and again in people who older than 65 years old. In the United States, the approximate acute leukemia ratio in children is 1:25,000. In Thailand (2003), the approximate acute leukemia is 53% of all childhood cancers. The development of acute leukemia has been associated with potential etiologic factors such as Genetic syndromes, Medications (Topoisomerase inhibitors and Alkylating agents) and Viruses (Epstein-Barr virus, HTLV-1) [2].