Although only calcium is routinely used during prenatal control in many countries, given its undoubted utility as nutritional intervention, its use alone to prevent preeclampsia has had contradictory results since 2001 3,4,12. The pregnant women included in this study were the representative number sufficient to detect differences in a pregnant population with high educational level and adequate income, given that it is a population ensured within the Colombian Social Security System, a group in which the opportunity is guaranteed in medical care and its quality.