When the body of infection, disease, or due to some reasons. The stimulate the brain and hypothalamus respond by adjusting the temperature of the body to a higher level. The tissue to be increase in body temperature following the order of the brain"s blood vessels and muscles The vessel will shrink to prevent the heat spread out through the skin and lungs. The body temperature rises and make patients feel the cold from reducing the amount of blood ไปหล่อเลี้ยง. The different muscle"s contraction. Cause chills, all of which is "running a fever." But when the hypothalamus brain stimulation decreased. Cerebral cortex hypothalamus will respond with reduced body temperature.