Computational modeling is therefore essentiato both design time and cost reduction .Additionally, computers can aid in the automation of construction and the characterization of genetic parts. For instance, users can interrogate various behaviors of a device, such as its robustness and stability, on a highthrough put basis [11, 12]. They may occasionally identify unexpected behavior of the device through modeling and simulation that speed up the system construction process [4]. Such steps help address crucial issuessuch as optimal input concentration, reaction durationor requirement for steady or dynamic measurements [4].Wellfounded estimates from models allow the building of more predictable and reliable genetic devices to facilitatethe planning of specific validation experiments