Somatuline is supplied in strengths of 60 mg, 90 mg and 120 mg designed for subcutaneous injection. The recommended initial dose of the drug in subjects with moderate and severe renal or moderate and severe hepatic impairment is 60 mg at 4 week intervals for 3 months followed by dose adjustment as described below. The recommended initial dose of the drug for all other subjects is 90 mg at 4 week intervals for 3 months. After 3 months the dosage may be adjusted as follows: