A sizing process is performed on most papers to provide resistance to liquid penetration. Internal sizing with a rosin acid sizing agent or Alkyl Ketene Dimer (AKD) and Alkenyl Succinic Anhydride (ASA) is performed at the wet end, but surface sizing uses mainly modified starches to form a water-repellent film on the paper surface [1]. It is a common practice to transform the hydrophilic papers into the water-repellent ones by the sizing process. On the other hand, there is a need to find a new and easy method to modify the surface properties of the papers in other industries, particularly nano-technology. This can be accomplished by using self-assembled monolayer (SAM) which is spontaneously formed monolayer and can produce needed surface properties on substrate. The SAM has high chemical and physical stabilities and a variety of the desired surface properties. For example, hydrophobic surfaces can be produced with the chemical treatment. Due to its advantageous properties, the SAM has potential applications in the surface modification, chemical and biosensor, and corrosion prevention [2–4]. The unique properties of the SAM can be utilized for the formation of the hydrophobic surface on papers.