This article present a connection between oral health and physical health. Scientific research and patient case study of Samaha have connected periodontal disease with other diseases. Besides the connection was affirmed in 1996 by dental researchers Genco and Offenbacher, who revealed the results of their work to the American Academy of Periodontology. Since then, acknowledged of the connection accepted that the mouth can become a source of disease or pathological processes affecting other parts of the body. It is concluded that the mouth can reflected disease in other parts of the body.