Hence, in this study we examined the in vitro antimicrobial activities of H. sabdariffa extract against uropathogenic bacteria isolated from recurrent Urinary tract infections. H. sabdariffa is a common herbal drink consumed both hot and cold by people around the world and is used in traditional medicine for the treatment of hypertension and Urinary tract infections.. The infusion is, usually known as karkade or red tea, made from the calyces of the H. sabdariffa. The red calyces are the part of the plant with commercial interest and are rich in organic acids, minerals, anthocyanins, and other phenolic compounds[12]. The calyces are potentially a good source for antioxidant agents such as anthocyanins and ascorbic acid[13]. In animal models, extracts of this flower have demonstrated hypocholesterolemic and antihypertensive properties[9]. Relatively few studies have been carried out to evaluate the antimicrobial activities of this plant against some sort of common human pathogens.