Kaempferia parviflora Wall. Ex. Baker (Krachaidum) has long been used among Thai men for sexual
enhancement. The aim of this study was to determine the effect of K. parviflora ethanolic extract on the sexual
behavior of male rats and its toxicity. The experiment was divided into three groups of rats given K. parviflora
extract at doses of 60, 120, and 240 mg/kg BW for 60 days, whilst a control group received distilled water at 1
ml/day per oral. The results showed that all groups of male rats had significantly higher courtship behavior during
the first 10-minute period of observation than in the 2nd and 3rd 10-minute periods, except those receiving the
highest dose of K. parviflora. They revealed the same amount of courtship behavior throughout a whole 30-minute
period, which was significantly lower than the control group. There was no significant difference between treated
and control groups in other sexual behaviors; mount frequency (MF), intromission frequency (IF), mount latency
(ML), or intromission latency (IL). Toxicological study revealed no significant difference of hemoglobin, WBC
or differential cell count. All dosages had no effect on kidney and liver function, according to the normal values
of blood urea nitrogen (BUN), creatinine (Crea), aspartate aminotransferase (AST) and alanine aminotransferase
(ALT). Nevertheless, the histopathological study showed a morphological change in the liver. It was concluded
that K. parviflora extract at 240 mg/kg BW reduced the time in the first 10 mintues of rat courtship behavior
and the use of high and chronic doses of K. parviflora in humans should be considered inadvisable.
Kaempferia parviflora Wall. Ex. Baker (Krachaidum) has long been used among Thai men for sexualenhancement. The aim of this study was to determine the effect of K. parviflora ethanolic extract on the sexualbehavior of male rats and its toxicity. The experiment was divided into three groups of rats given K. parvifloraextract at doses of 60, 120, and 240 mg/kg BW for 60 days, whilst a control group received distilled water at 1ml/day per oral. The results showed that all groups of male rats had significantly higher courtship behavior duringthe first 10-minute period of observation than in the 2nd and 3rd 10-minute periods, except those receiving thehighest dose of K. parviflora. They revealed the same amount of courtship behavior throughout a whole 30-minuteperiod, which was significantly lower than the control group. There was no significant difference between treatedand control groups in other sexual behaviors; mount frequency (MF), intromission frequency (IF), mount latency(ML), or intromission latency (IL). Toxicological study revealed no significant difference of hemoglobin, WBCor differential cell count. All dosages had no effect on kidney and liver function, according to the normal valuesof blood urea nitrogen (BUN), creatinine (Crea), aspartate aminotransferase (AST) and alanine aminotransferase(ALT). Nevertheless, the histopathological study showed a morphological change in the liver. It was concludedthat K. parviflora extract at 240 mg/kg BW reduced the time in the first 10 mintues of rat courtship behaviorand the use of high and chronic doses of K. parviflora in humans should be considered inadvisable.
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