Therapy and Outcome
All 10 patients with IE either completed a 42-day
course of intravenous antibiotics (9 patients) or died
(1 patient). One patient with endocarditis developed
recurrent bacteremia after completion of therapy.
The patients who did not have evidence of metastatic
infection received an average of 15 days of antibiotic
therapy.
Patient outcomes are reported in Table 4. The
1-year mortality rate for children with SAB was 18%.
The 1-year mortality rate for patients with IE was
40%, whereas it was 12% for patients without IE. Of
the 9 deaths, 4 were in children who were treated for
IE; the other 5 children had multiorgan failure in the
setting of chronic disease.