Obstructive Sleep Apnea (OSA), the most common form of sleep related breathing disorder, is characterized by repetitive episodes of upper airway obstruction resulting in partial or complete airflow cessation, causing oxygen desaturation and arousal from sleep (Table 3). Affected individuals and their bed partners report snoring, witnessed apneas, nocturnal awakenings, nocturia, unrefreshing sleep, as well as excessive daytime sleepiness and fatigue. The disorder is diagnosed by overnight PSG and severity is determined primarily by the apnea-hypopnea index (AHI; mild: 5-