Mutation, Population Genetic Models of
Abstract
Author gives an overview of population genetic models of mutation. Early bi-allelic models have remained in use for nearly 100 years owing to their applicability to a wide range of problems. However, extensions to multi-allelic models have proven necessary to address question in both molecular and phenotypic evolution.
Keywords
Allele frequencyAllelesDNAHeterozygosityKimuraModelsMutationMutation-drift balanceMutation rateMutation-selection balanceNucleotide diversityPolymorphism