The RSM is an effective statistical technique for developing,improving, and optimizing complex processes [12,13].The RSM is a collection of statistical and mathematical techniques that are useful for analyzing the effects of several independent variables on a response [14]. This process usually employs a low-order polynomial equation in a predetermined region of the independent variables, which is later analyzed to locate the optimum values of the independent variables for the best response [15]. The RSM defines the effect of the independent variablesdalone or in combinationdin the processes.In addition to analyzing the effects of the independent variables, this experimental methodology also generates
mathematical models [14].