a b s t r a c tIn thisworktheelectr

a b s t r a c t
In thisworktheelectrochemicalbehaviorofsubstancesofenvironmentalconcern[bentazone,atrazine,
carbamazepine, phenytoinanditsmetabolite5-(4-hydroxyphenyl)-5-phenylhydantoin,HPPH]ona
glassy carbonworkingelectrode(Ag/AgClreferenceelectrode)wasstudiedwiththeaimtodevelopa
HPLC methodcoupledwithamperometricdetection.Constantpotential(DC),pulsedamperometric
detection modeswerestudied.Forthepulsedmode,severalwaveformsweresetandinvestigated.
Detection conditionswereoptimizedasafunctionofeluentpH.
In ordertoreducethelimitsofdetectionandtoanalyzenaturalwatersamples,aSPEprotocolwas
optimized tobecoupledtothedevelopedprocedure.Forthisaim, five sorbentsofdifferentphysico-
chemical characteristicsweretestedoptimizingarecoveryprocedureforeachofthecartridgeevaluated.
At theoptimizedSPEconditions,recoverieswereincludedintherange(R¼90.2–100.5%forallthe
analytes,withexcellentreproducibility(o%, n¼3). Themethoddetectionlimitsobtainedbypulsed
amperometry aftertheSPEprotocol(preconcentrationfactor100)were113ngL1 (0.47nmolL1),
67 ngL1 (0.25 nmolL1), 234ngL1 (1.1nmolL1), forbentazone,HPPHandcarbamazepine,respec-
tively.Robustnessofthemethodwasassessedforeachanalyteataconcentrationlevelcorrespondingto
about threetimesthelimitofdetection,throughtheevaluationofintra-day(n¼13)andinter-daytests
(4 days, n¼52). Finallythemethodwassuccessfullyappliedfortheanalysisofariversample(PoRiver,
Turin, Italy).

ผลลัพธ์ (ไทย) 2:

นามธรรม
ใน
phenytoinanditsmetabolite5- (4 hydroxyphenyl) -5-phenylhydantoin, HPPH] ฯ
carbonworkingelectrode คล้ายแก้ว (AG / AgClreferenceelectrode) wasstudiedwiththeaimtodevelopa
HPLC methodcoupledwithamperometricdetection.Constantpotential (DC) pulsedamperometric
modeswerestudied.Forthepulsedmode ตรวจสอบ severalwaveformsweresetandinvestigated
ตรวจ conditionswereoptimizedasafunctionofeluentpH
ใน ordertoreducethelimitsofdetectionandtoanalyzenaturalwatersamples, aSPEprotocolwas
เหมาะสม tobecoupledtothedevelopedprocedure.Forthisaim ห้า sorbentsofdifferentphysico-
เคมี characteristicsweretestedoptimizingarecoveryprocedureforeachofthecartridgeevaluated
ที่
n¼3) Themethoddetectionlimitsobtainedbypulsed
amperometry aftertheSPEprotocol (preconcentrationfactor100) were113ngL? 1 (0.47nmolL? 1),
67 NGL? 1 (0.25 nmolL? 1), 234ngL? 1 (1.1nmolL? 1) threetimesthelimitofdetection, throughtheevaluationofintra วัน (n¼13) andinter daytests- (4 วัน, n¼52) Finallythemethodwassuccessfullyappliedfortheanalysisofariversample (PoRiver, ตูริน, อิตาลี)

ผลลัพธ์ (ไทย) 3:

B S T R A C T
bentazone อาทราซีนใน thisworktheelectrochemicalbehaviorofsubstancesofenvironmentalconcern [ ,
phenytoinanditsmetabolite5 โรคผิวหนัง , , - ( 4-hydroxyphenyl ) - 5-phenylhydantoin hpph ] , Ona
เหลือบ carbonworkingelectrode ( Ag / agclreferenceelectrode ) wasstudiedwiththeaimtodevelopa
4 methodcoupledwithamperometricdetection . constantpotential ( DC ) , pulsedamperometric
ตรวจจับ modeswerestudied .forthepulsedmode severalwaveformsweresetandinvestigated , conditionswereoptimizedasafunctionofeluentph .

ในการตรวจจับ ordertoreducethelimitsofdetectionandtoanalyzenaturalwatersamples aspeprotocolwas
, เหมาะ tobecoupledtothedevelopedprocedure . forthisaim ห้า sorbentsofdifferentphysico -

characteristicsweretestedoptimizingarecoveryprocedureforeachofthecartridgeevaluated เคมี .ที่ theoptimizedspeconditions recoverieswereincludedintherange ( R ) , ¼ 90.2 100.5 % forallthe
สาร withexcellentreproducibility , ( O ( n ¼ 3 ) themethoddetectionlimitsobtainedbypulsed
แอมเพอโรเมทรี afterthespeprotocol ( preconcentrationfactor100 ) were113ngl  1 ( 0.47nmoll  1 ) ,
67 ปตท.  1 ( 0.25 nmoll  1 ) 234ngl  1 ( 1.1nmoll  1 ) forbentazone hpphandcarbamazepine respec -
, , มี .robustnessofthemethodwasassessedforeachanalyteataconcentrationlevelcorrespondingto
เกี่ยวกับ threetimesthelimitofdetection throughtheevaluationofintra , วัน ( N ¼ 13 ) andinter daytests
( 4 วัน ¼ ( 52 ) finallythemethodwassuccessfullyappliedfortheanalysisofariversample ( poriver
, Turin , อิตาลี )