Objective , To investigate the current antimicrobial resistance patterns of E.coli isolated from pig at the slaughter in Khon Kaen province . The reason that we chose this study because it’s easy to collect sample , good representative sample and why we study in fattening pigs . Because the pigs is full term of use antimicrobial such as antimicrobial for treat , add in food for growth promotor or use by prophylaxis .