GLUT2 also carries glucosamine.[8]
When the glucose concentration in the lumen of the small intestine goes above 30mM, such as occurs in the fed-state, GLUT2 is up-regulated at the brush border membrane, enhancing the capacity of glucose transport. Basolateral GLUT2 in enterocytes also aids in the transport of fructose into the bloodstream through glucose-dependent cotransport.