The HDAC Fluorescent Activity Assay/Drug Discovery
Kit is a complete assay system designed to measure
histone deacetylase (HDAC) activity in cell or nuclear
extracts, immunoprecipitates or purified enzymes. It
comes in a convenient 96-well format, with all reagents
necessary for fluorescent HDAC activity measurements
and calibration of the assay. In addition, a HeLa nuclear
extract, rich in HDAC activity, is included with the kit.
The extract is useful as either a positive control or as the
source of HDAC activity for inhibitor/drug screening.
Also included is the potent HDAC inhibitor, Trichostatin
A, which may be used as model inhibitor.