Hp was detected by Immune-turbidimetric method.
CEA, NSE and CYFRA21-1 were detected by
Chemiluminescence immunoassay. Critical value of Hp,
CEA, NSE and CYFRA21-1 was 2.0g/L, 9.8μg/L, 12μg/L
and 3.5μg/L. Positive test was set if serum specimen
detected greater than the above value. In combined
detection, the general was judged as positive as long as
any one marker was positive and the general was judged
as negative when all above four markers were negative.