By combining REDCap, a validated, low-cost data capture tool with built-in compliance components, with the existing RMT model of comprehensive, flexible research support infrastructure, we have decreased disparities in research support across funding mechanisms and achieved high initial rates of customer satisfaction across our institution. The RMT model has the potential for adoption throughout the CTSA consortium and other academic health and science systems, and may serve as a vehicle for providing cost-effective improvements to the quality and security of clinical and translational research conducted at these institutions.