Studies focusing on the long-term stability of RGO in predominantly oxidative environments are lacking. However, the reductive decomposition of RGO has been reported.49 Several of the previously referred electrocatalytic or photocatalytic applications for RGO involve OH• as a primary or side reaction product. For example, TiO2 photocatalytic degradation of pollutants has been a popular line of study50−52 and is primarily driven by evolution of OH• from the TiO2 valence band holes.53−55 Oxygen reduction reactions at the cathode of fuel cells can also lead to OH• formation as a product of side reactions.56−58 Short-term performance enhancement seen in such applications has led numerous reports, including some of our own, to tout RGO as an exceptional conductive support that promotes efficient charge separation and charge transport behavior. However, in the long view, the question that one encounters is whether GO and RGO can withstand the onslaught of highly reactive species such as OH• radicals. The residual hydrogens bonded to the surface and edges of RGO59 can lead one to envision a single RGO sheet as many fused polyaromatic hydrocarbons (PAHs). Because PAHs are of significant environmental concern, emphasis must be placed on the long-term impact of RGO in applications where highly oxidizing species may promote disintegration of RGO into PAH-like fragments.