In acutetoxicitystudy,thedoseof2000mg/kgofANEdidnot
cause mortalityinmiceorratsduring14daysobservation.The
mice andratsdidnotshowanysignsoftoxicityorchangein
generalbehaviororotherphysiologicalactivities.Fortherestof
the study,weused250and500mg/kgofANEfromourprevious
findings