Objective: To document traditional medicinal plants knowledge used in treating skin diseases at Hyderabad Karnataka Region. Methods: The information on the use of medicinal plants in the treatment of gathered from traditional herbal healers and other villagers through interviews. skin diseases was Results: A total of 60 plants species belonging to 57 genera and 34 families were found useful apnrodb haebrleew diothsa dgees acnridb eddu rtahteiomn aolfo tnrge awtmithe ntth.e S emveetrhaol dn eowf d frinudg ipnrgesp oanra tthioen t,r amdoitdieo noafl ardumrailn pisrtarcattiicoens, were reported. Conclusions: The present study revealed that the Hyderabad Karnataka rural people is primarily dependent on medicinal plants for treating skin diseases.