An increase in the number of cells in G2-M and sub
G0–G1 phases was observed, indicating the cell cycle arrest at
G2-M phase and subsequent apoptosis. Percentage of cells in sub
G0–G1 phase was found to be 41% in the case of MCF-7 cells when
treated with MLL and cisplatin. Sub G0–G1 value of 12% and 33%
were observed in HCT-15 treated with MLL and cisplatin,
respectively.