Most of the studies on leech therapy are found for plastic surgery and pain reduction in osteoarthritis. The bite of a leech is actually painless. All ancient civilizations practiced bloodletting including Indian and Greek civilizations. The use of leeches in modern medicine made its comeback in the 1980s after years of decline, with the advent of microsurgery such as plastic and reconstructive surgeries. Acharya Susruta mentions leech therapy as a mainstay in pancakarma and is aimed at blood vitiated by pitta, deep seated vitiated pitta disease, pain, etc. [