Glacial acetic acid and acetic anhydride were purchased from El-Nasr Pharmaceuticals and Chemicals Company, Cairo, Egypt. Sulfuric acid was used as a catalyst and for the acid resistance test; polyethylene glycol 600 was used as a plasticizer; and acetone was used as a solvent. Sodium hydroxide, lead acetate, ferrous sulfate and tri- sodium orthophosphate were used for testing acids, alkalis and salts to the produced CA’s resistance. They were purchased from Sigma–Aldrich Corporation, USA.