The rest material after extraction of antimicrobial compounds
is still valuable material for biomedical application – can be used
as a natural drug carrier as a substance which are added to pharmaceuticals
to improve it delivery and effectiveness. After alkali
hydrolysis, performed to rely of well bounded compounds, the
shives cellulose, the basic structural component of flax shives and
fiber, with free functional groups/bounds will be obtained. Such
active groups can bond pharmaceuticals. After process of 20 h of
ball-milling treatment the decreased particle size will be obtained.
This method results in structural changes in biopolymers (cellulose,
hemicellulose, pectin, and lignin) and increasing of functional
group content(Dyminska et al., 2012). The pilot study confirms this
hypothesis that fibers and shives, initially subjected alkali hydrolysis
and after that micronized effectively binds hydrophobic and
hydrophilic compounds (data unpublished).
The rest material after extraction of antimicrobial compoundsis still valuable material for biomedical application – can be usedas a natural drug carrier as a substance which are added to pharmaceuticalsto improve it delivery and effectiveness. After alkalihydrolysis, performed to rely of well bounded compounds, theshives cellulose, the basic structural component of flax shives andfiber, with free functional groups/bounds will be obtained. Suchactive groups can bond pharmaceuticals. After process of 20 h ofball-milling treatment the decreased particle size will be obtained.This method results in structural changes in biopolymers (cellulose,hemicellulose, pectin, and lignin) and increasing of functionalgroup content(Dyminska et al., 2012). The pilot study confirms thishypothesis that fibers and shives, initially subjected alkali hydrolysisand after that micronized effectively binds hydrophobic andhydrophilic compounds (data unpublished).
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