Conclusion:
In conclusion, this study shows that global ventricular
function is depressed in scleroderma
patients. A PW TDI analysis complements conventional
echocardiography in the detection of
subclinical biventricular impairment in patients
with scleroderma. Simultaneous LV and RV systolic
function evaluated by measuring IVA was
found to be lower in patients with scleroderma
and this may be important for the early detection
of myocardial involvement. In this study, MPI
was measured not only by conventional Doppler
but also by TDI for each ventricle, in contrast to
previous studies. In scleroderma patients, MPI
values revealed the presence of global biventricular
dysfunction. The early echocardiographic
detection of cardiac involvement in scleroderma
patients is desirable for optimal treatment and
for implementation of preventive measures in the
early stages of the disease